Journal article
Adjunctive nutraceuticals with standard pharmacotherapies in bipolar disorder: A systematic review of clinical trials
J Sarris, D Mischoulon, I Schweitzer
Bipolar Disorders | Published : 2011
Abstract
Objective: Studies using augmentation of pharmacotherapies with nutraceuticals in bipolar disorder (BD) have been conducted and preliminary evidence in many cases appears positive. To date, however, no specialized systematic review of this area has been conducted. We present the first systematic review of clinical trials using nutrient-based nutraceuticals in combination with standard pharmacotherapies to treat BD. A subsequent aim of this report was to discuss posited underlying mechanisms of action. Methods: PubMed, CINAHL, Web of Science, and Cochrane Library databases, and grey literature were searched during mid-2010 for human clinical trials in English using nutraceuticals such as omeg..
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Grants
Awarded by Australian National Health and Medical Research Council (NHMRC)
Funding Acknowledgements
JS is funded by an Australian National Health and Medical Research Council Fellowship (NHMRC funding ID 628875) in a strategic partnership with The University of Melbourne and the Centre for Human Psychopharmacology at Swinburne University of Technology.DM has received research support from Nordic Naturals and Ganeden; has served as a consultant to Bristol-Myers Squibb; has received writing honoraria from Pamlab; has received royalties from Back Bay Scientific for PMS Escape, and royalties from Lippincott Williams & Wilkins for the textbook Natural Medications for Psychiatric Disorders: Considering the Alternatives; and he has received honoraria from Reed Medical Education (a company working as a logistics collaborator for the MGH Psychiatry Academy). The education programs conducted by the MGH Psychiatry Academy were supported through Independent Medical Education grants from pharmaceutical companies co-supporting programs along with participant tuition. Commercial entities currently supporting the MGH Psychiatry Academy are listed on the Academy's website http://www.mghcme.org. JS and IS have no conflicts of interest to report.